Mepacrine en es it fr

Mepacrine Brand names, Mepacrine Analogs

Mepacrine Brand Names Mixture

  • No information avaliable

Mepacrine Chemical_Formula

C23H30ClN3O

Mepacrine RX_link

No information avaliable

Mepacrine fda sheet

Mepacrine msds (material safety sheet)

Mepacrine MSDS

Mepacrine Synthesis Reference

No information avaliable

Mepacrine Molecular Weight

399.957 g/mol

Mepacrine Melting Point

248-250 oC

Mepacrine H2O Solubility

Slight

Mepacrine State

Solid

Mepacrine LogP

5.388

Mepacrine Dosage Forms

Tablet

Mepacrine Indication

For the treatment of giardiasis and cutaneous leishmaniasis and the management of malignant effusions.

Mepacrine Pharmacology

Quinacrine has been used as an antimalarial drug and as an antibiotic. It is used to treat giardiasis, a protozoal infection of the intestinal tract, and certain types of lupus erythematosus, an inflammatory disease that affects the joints, tendons, and other connective tissues and organs. Quinacrine may be injected into the space surrounding the lungs to prevent reoccurrence of pneumothorax. The exact way in which quinacrine works is unknown. It appears to interfere with the parasite's metabolism.

Mepacrine Absorption

Absorbed rapidly from the gastrointestinal tract following oral administration.

Mepacrine side effects and Toxicity

Oral, rat: LD50 = 900 mg/kg; Oral, mouse: LD50 = 1000 mg/kg. Symptoms of overdose include seizures, hypotension, cardiac arrhythmias, and cardiovascular collapse.

Mepacrine Patient Information

This medication is best taken after meals with a full glass of water, fruit juice, or tea, unless your doctor instructs otherwise. Tablets may be crushed and mixed with chocolate syrup, honey, or jam for persons who cannot stand the bitter taste or have difficulty swallowing tablets. If you miss a dose, take it as soon as you remember. If it is near the time for the next dose, skip the missed dose and resume your regular dosage schedule. Do not double the next dose. Take it as prescribed for the full treatment period, even if you feel better before the scheduled end of therapy.

Mepacrine Organisms Affected

Parasitic protozoa and helminths