Atebrine

Atebrine Brand names, Atebrine Analogs

Atebrine Brand Names Mixture

No information avaliable

Atebrine Chemical_Formula

C₂₃H₃₀ClN₃O

Atebrine RX_link

No information avaliable

Atebrine fda sheet

Atebrine msds (material safety sheet)

Atebrine MSDS

Atebrine Synthesis Reference

No information avaliable

Atebrine Molecular Weight

399.957 g/mol

Atebrine Melting Point

248-250 ^oC

Atebrine H₂O Solubility

Slight

Atebrine State

Solid

Atebrine LogP

5.388

Atebrine Dosage Forms

Tablet

Atebrine Indication

For the treatment of giardiasis and cutaneous leishmaniasis and the management of malignant effusions.

Atebrine Pharmacology

Quinacrine has been used as an antimalarial drug and as an antibiotic. It is used to treat giardiasis, a protozoal infection of the intestinal tract, and certain types of lupus erythematosus, an inflammatory disease that affects the joints, tendons, and other connective tissues and organs. Quinacrine may be injected into the space surrounding the lungs to prevent reoccurrence of pneumothorax. The exact way in which quinacrine works is unknown. It appears to interfere with the parasite's metabolism.

Atebrine Absorption

Absorbed rapidly from the gastrointestinal tract following oral administration.

Atebrine side effects and Toxicity

Oral, rat: LD₅₀ = 900 mg/kg; Oral, mouse: LD₅₀ = 1000 mg/kg. Symptoms of overdose include seizures, hypotension, cardiac arrhythmias, and cardiovascular collapse.

Atebrine Patient Information

This medication is best taken after meals with a full glass of water, fruit juice, or tea, unless your doctor instructs otherwise. Tablets may be crushed and mixed with chocolate syrup, honey, or jam for persons who cannot stand the bitter taste or have difficulty swallowing tablets. If you miss a dose, take it as soon as you remember. If it is near the time for the next dose, skip the missed dose and resume your regular dosage schedule. Do not double the next dose. Take it as prescribed for the full treatment period, even if you feel better before the scheduled end of therapy.

Atebrine Organisms Affected

Parasitic protozoa and helminths