PharmacyCodes



Atebrin en es it fr

Atebrin Brand names, Atebrin Analogs

Atebrin Brand Names Mixture

  • No information avaliable

Atebrin Chemical_Formula

C23H30ClN3O

Atebrin RX_link

No information avaliable

Atebrin fda sheet

Atebrin msds (material safety sheet)

Atebrin MSDS

Atebrin Synthesis Reference

No information avaliable

Atebrin Molecular Weight

399.957 g/mol

Atebrin Melting Point

248-250 oC

Atebrin H2O Solubility

Slight

Atebrin State

Solid

Atebrin LogP

5.388

Atebrin Dosage Forms

Tablet

Atebrin Indication

For the treatment of giardiasis and cutaneous leishmaniasis and the management of malignant effusions.

Atebrin Pharmacology

Quinacrine has been used as an antimalarial drug and as an antibiotic. It is used to treat giardiasis, a protozoal infection of the intestinal tract, and certain types of lupus erythematosus, an inflammatory disease that affects the joints, tendons, and other connective tissues and organs. Quinacrine may be injected into the space surrounding the lungs to prevent reoccurrence of pneumothorax. The exact way in which quinacrine works is unknown. It appears to interfere with the parasite's metabolism.

Atebrin Absorption

Absorbed rapidly from the gastrointestinal tract following oral administration.

Atebrin side effects and Toxicity

Oral, rat: LD50 = 900 mg/kg; Oral, mouse: LD50 = 1000 mg/kg. Symptoms of overdose include seizures, hypotension, cardiac arrhythmias, and cardiovascular collapse.

Atebrin Patient Information

This medication is best taken after meals with a full glass of water, fruit juice, or tea, unless your doctor instructs otherwise. Tablets may be crushed and mixed with chocolate syrup, honey, or jam for persons who cannot stand the bitter taste or have difficulty swallowing tablets. If you miss a dose, take it as soon as you remember. If it is near the time for the next dose, skip the missed dose and resume your regular dosage schedule. Do not double the next dose. Take it as prescribed for the full treatment period, even if you feel better before the scheduled end of therapy.

Atebrin Organisms Affected

Parasitic protozoa and helminths