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Atabrine Brand names, Atabrine Analogs

Atabrine Brand Names Mixture

  • No information avaliable

Atabrine Chemical_Formula


Atabrine RX_link

No information avaliable

Atabrine fda sheet

Atabrine msds (material safety sheet)

Atabrine MSDS

Atabrine Synthesis Reference

No information avaliable

Atabrine Molecular Weight

399.957 g/mol

Atabrine Melting Point

248-250 oC

Atabrine H2O Solubility


Atabrine State


Atabrine LogP


Atabrine Dosage Forms


Atabrine Indication

For the treatment of giardiasis and cutaneous leishmaniasis and the management of malignant effusions.

Atabrine Pharmacology

Quinacrine has been used as an antimalarial drug and as an antibiotic. It is used to treat giardiasis, a protozoal infection of the intestinal tract, and certain types of lupus erythematosus, an inflammatory disease that affects the joints, tendons, and other connective tissues and organs. Quinacrine may be injected into the space surrounding the lungs to prevent reoccurrence of pneumothorax. The exact way in which quinacrine works is unknown. It appears to interfere with the parasite's metabolism.

Atabrine Absorption

Absorbed rapidly from the gastrointestinal tract following oral administration.

Atabrine side effects and Toxicity

Oral, rat: LD50 = 900 mg/kg; Oral, mouse: LD50 = 1000 mg/kg. Symptoms of overdose include seizures, hypotension, cardiac arrhythmias, and cardiovascular collapse.

Atabrine Patient Information

This medication is best taken after meals with a full glass of water, fruit juice, or tea, unless your doctor instructs otherwise. Tablets may be crushed and mixed with chocolate syrup, honey, or jam for persons who cannot stand the bitter taste or have difficulty swallowing tablets. If you miss a dose, take it as soon as you remember. If it is near the time for the next dose, skip the missed dose and resume your regular dosage schedule. Do not double the next dose. Take it as prescribed for the full treatment period, even if you feel better before the scheduled end of therapy.

Atabrine Organisms Affected

Parasitic protozoa and helminths