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Periactinol Brand names, Periactinol Analogs

Periactinol Brand Names Mixture

  • No information avaliable

Periactinol Chemical_Formula


Periactinol RX_link

Periactinol fda sheet

Periactinol msds (material safety sheet)

Periactinol MSDS

Periactinol Synthesis Reference

No information avaliable

Periactinol Molecular Weight

287.398 g/mol

Periactinol Melting Point

215-217 oC

Periactinol H2O Solubility


Periactinol State


Periactinol LogP


Periactinol Dosage Forms

Syrup; Tablet

Periactinol Indication

For treatment of perennial and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis due to inhalant allergens and foods, mild uncomplicated allergic skin manifestations of urticaria and angioedema, amelioration of allergic reactions to blood or plasma, cold urticaria, dermatographism, and as therapy for anaphylactic reactions adjunctive to epinephrine.

Periactinol Pharmacology

Cyproheptadine is a piperidine antihistamine. Unlike other antihistamines, this drug also antagonizes serotonin receptors. This action makes Cyproheptadine useful in conditions such as vascular headache and anorexia. Cyproheptadine does not prevent the release of histamine but rather competes with free histamine for binding at HA-receptor sites. Cyproheptadine competitively antagonizes the effects of histamine on HA-receptors in the GI tract, uterus, large blood vessels, and bronchial smooth muscle. Most antihistamines possess significant anticholinergic properties, but Cyproheptadine exerts only weak anticholinergic actions. Blockade of central muscarinic receptors appears to account for Cyproheptadine's antiemetic effects, although the exact mechanism is unknown. Cyproheptadine also competes with serotonin at receptor sites in smooth muscle in the intestines and other locations. Antagonism of serotonin on the appetite center of the hypothalamus may account for Cyproheptadine's ability to stimulate appetite. Cyproheptadine also has been used to counter vascular headaches, which many believe are caused by changes in serotonin activity, however it is unclear how Cyproheptadine exerts a beneficial effect on this condition.

Periactinol Absorption

Well absorbed after oral administration.

Periactinol side effects and Toxicity

No information avaliable

Periactinol Patient Information

Antihistamines may diminish mental alertness; conversely, particularly, in the young child, they may occasionally produce excitation. Patients should be warned about engaging in activities requiring mental alertness and motor coordination, such as driving a car or operating machinery.

Periactinol Organisms Affected

Humans and other mammals