Cyproheptadine Hcl
Cyproheptadine Hcl Brand names, Cyproheptadine Hcl Analogs
Cyproheptadine Hcl Brand Names Mixture
- No information avaliable
Cyproheptadine Hcl Chemical_Formula
C21H21N
Cyproheptadine Hcl RX_link
http://www.rxlist.com/cgi/generic2/cyprohept.htm
Cyproheptadine Hcl fda sheet
Cyproheptadine Hcl msds (material safety sheet)
Cyproheptadine Hcl Synthesis Reference
No information avaliable
Cyproheptadine Hcl Molecular Weight
287.398 g/mol
Cyproheptadine Hcl Melting Point
215-217 oC
Cyproheptadine Hcl H2O Solubility
Soluble
Cyproheptadine Hcl State
Solid
Cyproheptadine Hcl LogP
4.682
Cyproheptadine Hcl Dosage Forms
Syrup; Tablet
Cyproheptadine Hcl Indication
For treatment of perennial and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis due to inhalant allergens and foods, mild uncomplicated allergic skin manifestations of urticaria and angioedema, amelioration of allergic reactions to blood or plasma, cold urticaria, dermatographism, and as therapy for anaphylactic reactions adjunctive to epinephrine.
Cyproheptadine Hcl Pharmacology
Cyproheptadine is a piperidine antihistamine. Unlike other antihistamines, this drug also antagonizes serotonin receptors. This action makes Cyproheptadine useful in conditions such as vascular headache and anorexia. Cyproheptadine does not prevent the release of histamine but rather competes with free histamine for binding at HA-receptor sites. Cyproheptadine competitively antagonizes the effects of histamine on HA-receptors in the GI tract, uterus, large blood vessels, and bronchial smooth muscle. Most antihistamines possess significant anticholinergic properties, but Cyproheptadine exerts only weak anticholinergic actions. Blockade of central muscarinic receptors appears to account for Cyproheptadine's antiemetic effects, although the exact mechanism is unknown. Cyproheptadine also competes with serotonin at receptor sites in smooth muscle in the intestines and other locations. Antagonism of serotonin on the appetite center of the hypothalamus may account for Cyproheptadine's ability to stimulate appetite. Cyproheptadine also has been used to counter vascular headaches, which many believe are caused by changes in serotonin activity, however it is unclear how Cyproheptadine exerts a beneficial effect on this condition.
Cyproheptadine Hcl Absorption
Well absorbed after oral administration.
Cyproheptadine Hcl side effects and Toxicity
No information avaliable
Cyproheptadine Hcl Patient Information
Antihistamines may diminish mental alertness; conversely, particularly, in the young child, they may occasionally produce excitation. Patients should be warned about engaging in activities requiring mental alertness and motor coordination, such as driving a car or operating machinery.
Cyproheptadine Hcl Organisms Affected
Humans and other mammals
