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Cypoheptadine Brand names, Cypoheptadine Analogs

Cypoheptadine Brand Names Mixture

  • No information avaliable

Cypoheptadine Chemical_Formula


Cypoheptadine RX_link

Cypoheptadine fda sheet

Cypoheptadine msds (material safety sheet)

Cypoheptadine MSDS

Cypoheptadine Synthesis Reference

No information avaliable

Cypoheptadine Molecular Weight

287.398 g/mol

Cypoheptadine Melting Point

215-217 oC

Cypoheptadine H2O Solubility


Cypoheptadine State


Cypoheptadine LogP


Cypoheptadine Dosage Forms

Syrup; Tablet

Cypoheptadine Indication

For treatment of perennial and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis due to inhalant allergens and foods, mild uncomplicated allergic skin manifestations of urticaria and angioedema, amelioration of allergic reactions to blood or plasma, cold urticaria, dermatographism, and as therapy for anaphylactic reactions adjunctive to epinephrine.

Cypoheptadine Pharmacology

Cyproheptadine is a piperidine antihistamine. Unlike other antihistamines, this drug also antagonizes serotonin receptors. This action makes Cyproheptadine useful in conditions such as vascular headache and anorexia. Cyproheptadine does not prevent the release of histamine but rather competes with free histamine for binding at HA-receptor sites. Cyproheptadine competitively antagonizes the effects of histamine on HA-receptors in the GI tract, uterus, large blood vessels, and bronchial smooth muscle. Most antihistamines possess significant anticholinergic properties, but Cyproheptadine exerts only weak anticholinergic actions. Blockade of central muscarinic receptors appears to account for Cyproheptadine's antiemetic effects, although the exact mechanism is unknown. Cyproheptadine also competes with serotonin at receptor sites in smooth muscle in the intestines and other locations. Antagonism of serotonin on the appetite center of the hypothalamus may account for Cyproheptadine's ability to stimulate appetite. Cyproheptadine also has been used to counter vascular headaches, which many believe are caused by changes in serotonin activity, however it is unclear how Cyproheptadine exerts a beneficial effect on this condition.

Cypoheptadine Absorption

Well absorbed after oral administration.

Cypoheptadine side effects and Toxicity

No information avaliable

Cypoheptadine Patient Information

Antihistamines may diminish mental alertness; conversely, particularly, in the young child, they may occasionally produce excitation. Patients should be warned about engaging in activities requiring mental alertness and motor coordination, such as driving a car or operating machinery.

Cypoheptadine Organisms Affected

Humans and other mammals