Percorten
Brand names,
Percorten
Analogs
Percorten
Brand Names Mixture
Percorten
Chemical_Formula
C26H38O4
Percorten
RX_link
No information avaliable
Percorten
fda sheet
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msds (material safety sheet)
Percorten
Synthesis Reference
No information avaliable
Percorten
Molecular Weight
414.578 g/mol
Percorten
Melting Point
No information avaliable
Percorten
H2O Solubility
Insoluble
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State
Solid
Percorten
LogP
5.544
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Dosage Forms
Cream; Suspension; Implantation; Pellet
Percorten
Indication
For treatment of adrenocortical insufficiency especially in multiple sclerosis, congenital cerebral palsy, polyarteritis nodosa, and rheumatoid arthritis.
Percorten
Pharmacology
Used to treat adrenocortical insufficiency, desoxycorticosterone pivalate is a mineralocorticoid hormone and an analogue of desoxycorticosterone. It primarily acts on the metabolism of sodium, potassium and water. When the drug is given, there is decreased excretion of sodium accompanied by increased excretion of potassium; the concentration of sodium in the blood is thereby increased whereas that of potassium is decreased. There is a concomitant increase in the volume of blood and extracellular fluids, with a fall in hematocrit. It increases the rate of renal tubular absorption of sodium.
Percorten
Absorption
No information avaliable
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side effects and Toxicity
Symptoms of overdose include polyuria, polydipsia, increased blood volume, edema, and cardiac enlargement.
Percorten
Patient Information
No information avaliable
Percorten
Organisms Affected
Humans and other mammals