Deoxycortone Trimethylacetate
Brand names,
Deoxycortone Trimethylacetate
Analogs
Deoxycortone Trimethylacetate
Brand Names Mixture
Deoxycortone Trimethylacetate
Chemical_Formula
C26H38O4
Deoxycortone Trimethylacetate
RX_link
No information avaliable
Deoxycortone Trimethylacetate
fda sheet
Deoxycortone Trimethylacetate
msds (material safety sheet)
Deoxycortone Trimethylacetate
Synthesis Reference
No information avaliable
Deoxycortone Trimethylacetate
Molecular Weight
414.578 g/mol
Deoxycortone Trimethylacetate
Melting Point
No information avaliable
Deoxycortone Trimethylacetate
H2O Solubility
Insoluble
Deoxycortone Trimethylacetate
State
Solid
Deoxycortone Trimethylacetate
LogP
5.544
Deoxycortone Trimethylacetate
Dosage Forms
Cream; Suspension; Implantation; Pellet
Deoxycortone Trimethylacetate
Indication
For treatment of adrenocortical insufficiency especially in multiple sclerosis, congenital cerebral palsy, polyarteritis nodosa, and rheumatoid arthritis.
Deoxycortone Trimethylacetate
Pharmacology
Used to treat adrenocortical insufficiency, desoxycorticosterone pivalate is a mineralocorticoid hormone and an analogue of desoxycorticosterone. It primarily acts on the metabolism of sodium, potassium and water. When the drug is given, there is decreased excretion of sodium accompanied by increased excretion of potassium; the concentration of sodium in the blood is thereby increased whereas that of potassium is decreased. There is a concomitant increase in the volume of blood and extracellular fluids, with a fall in hematocrit. It increases the rate of renal tubular absorption of sodium.
Deoxycortone Trimethylacetate
Absorption
No information avaliable
Deoxycortone Trimethylacetate
side effects and Toxicity
Symptoms of overdose include polyuria, polydipsia, increased blood volume, edema, and cardiac enlargement.
Deoxycortone Trimethylacetate
Patient Information
No information avaliable
Deoxycortone Trimethylacetate
Organisms Affected
Humans and other mammals