DOCP
Brand names,
DOCP
Analogs
DOCP
Brand Names Mixture
DOCP
Chemical_Formula
C26H38O4
DOCP
RX_link
No information avaliable
DOCP
fda sheet
DOCP
msds (material safety sheet)
DOCP
Synthesis Reference
No information avaliable
DOCP
Molecular Weight
414.578 g/mol
DOCP
Melting Point
No information avaliable
DOCP
H2O Solubility
Insoluble
DOCP
State
Solid
DOCP
LogP
5.544
DOCP
Dosage Forms
Cream; Suspension; Implantation; Pellet
DOCP
Indication
For treatment of adrenocortical insufficiency especially in multiple sclerosis, congenital cerebral palsy, polyarteritis nodosa, and rheumatoid arthritis.
DOCP
Pharmacology
Used to treat adrenocortical insufficiency, desoxycorticosterone pivalate is a mineralocorticoid hormone and an analogue of desoxycorticosterone. It primarily acts on the metabolism of sodium, potassium and water. When the drug is given, there is decreased excretion of sodium accompanied by increased excretion of potassium; the concentration of sodium in the blood is thereby increased whereas that of potassium is decreased. There is a concomitant increase in the volume of blood and extracellular fluids, with a fall in hematocrit. It increases the rate of renal tubular absorption of sodium.
DOCP
Absorption
No information avaliable
DOCP
side effects and Toxicity
Symptoms of overdose include polyuria, polydipsia, increased blood volume, edema, and cardiac enlargement.
DOCP
Patient Information
No information avaliable
DOCP
Organisms Affected
Humans and other mammals