Cortexone M
Brand names,
Cortexone M
Analogs
Cortexone M
Brand Names Mixture
Cortexone M
Chemical_Formula
C26H38O4
Cortexone M
RX_link
No information avaliable
Cortexone M
fda sheet
Cortexone M
msds (material safety sheet)
Cortexone M
Synthesis Reference
No information avaliable
Cortexone M
Molecular Weight
414.578 g/mol
Cortexone M
Melting Point
No information avaliable
Cortexone M
H2O Solubility
Insoluble
Cortexone M
State
Solid
Cortexone M
LogP
5.544
Cortexone M
Dosage Forms
Cream; Suspension; Implantation; Pellet
Cortexone M
Indication
For treatment of adrenocortical insufficiency especially in multiple sclerosis, congenital cerebral palsy, polyarteritis nodosa, and rheumatoid arthritis.
Cortexone M
Pharmacology
Used to treat adrenocortical insufficiency, desoxycorticosterone pivalate is a mineralocorticoid hormone and an analogue of desoxycorticosterone. It primarily acts on the metabolism of sodium, potassium and water. When the drug is given, there is decreased excretion of sodium accompanied by increased excretion of potassium; the concentration of sodium in the blood is thereby increased whereas that of potassium is decreased. There is a concomitant increase in the volume of blood and extracellular fluids, with a fall in hematocrit. It increases the rate of renal tubular absorption of sodium.
Cortexone M
Absorption
No information avaliable
Cortexone M
side effects and Toxicity
Symptoms of overdose include polyuria, polydipsia, increased blood volume, edema, and cardiac enlargement.
Cortexone M
Patient Information
No information avaliable
Cortexone M
Organisms Affected
Humans and other mammals