Deoxycortolone Pivalate
Brand names,
Deoxycortolone Pivalate
Analogs
Deoxycortolone Pivalate
Brand Names Mixture
Deoxycortolone Pivalate
Chemical_Formula
C26H38O4
Deoxycortolone Pivalate
RX_link
No information avaliable
Deoxycortolone Pivalate
fda sheet
Deoxycortolone Pivalate
msds (material safety sheet)
Deoxycortolone Pivalate
Synthesis Reference
No information avaliable
Deoxycortolone Pivalate
Molecular Weight
414.578 g/mol
Deoxycortolone Pivalate
Melting Point
No information avaliable
Deoxycortolone Pivalate
H2O Solubility
Insoluble
Deoxycortolone Pivalate
State
Solid
Deoxycortolone Pivalate
LogP
5.544
Deoxycortolone Pivalate
Dosage Forms
Cream; Suspension; Implantation; Pellet
Deoxycortolone Pivalate
Indication
For treatment of adrenocortical insufficiency especially in multiple sclerosis, congenital cerebral palsy, polyarteritis nodosa, and rheumatoid arthritis.
Deoxycortolone Pivalate
Pharmacology
Used to treat adrenocortical insufficiency, desoxycorticosterone pivalate is a mineralocorticoid hormone and an analogue of desoxycorticosterone. It primarily acts on the metabolism of sodium, potassium and water. When the drug is given, there is decreased excretion of sodium accompanied by increased excretion of potassium; the concentration of sodium in the blood is thereby increased whereas that of potassium is decreased. There is a concomitant increase in the volume of blood and extracellular fluids, with a fall in hematocrit. It increases the rate of renal tubular absorption of sodium.
Deoxycortolone Pivalate
Absorption
No information avaliable
Deoxycortolone Pivalate
side effects and Toxicity
Symptoms of overdose include polyuria, polydipsia, increased blood volume, edema, and cardiac enlargement.
Deoxycortolone Pivalate
Patient Information
No information avaliable
Deoxycortolone Pivalate
Organisms Affected
Humans and other mammals