DTMA
DTMA Brand names, DTMA Analogs
DTMA Brand Names Mixture
- No information avaliable
DTMA Chemical_Formula
C26H38O4
DTMA RX_link
No information avaliable
DTMA fda sheet
DTMA msds (material safety sheet)
DTMA Synthesis Reference
No information avaliable
DTMA Molecular Weight
414.578 g/mol
DTMA Melting Point
No information avaliable
DTMA H2O Solubility
Insoluble
DTMA State
Solid
DTMA LogP
5.544
DTMA Dosage Forms
Cream; Suspension; Implantation; Pellet
DTMA Indication
For treatment of adrenocortical insufficiency especially in multiple sclerosis, congenital cerebral palsy, polyarteritis nodosa, and rheumatoid arthritis.
DTMA Pharmacology
Used to treat adrenocortical insufficiency, desoxycorticosterone pivalate is a mineralocorticoid hormone and an analogue of desoxycorticosterone. It primarily acts on the metabolism of sodium, potassium and water. When the drug is given, there is decreased excretion of sodium accompanied by increased excretion of potassium; the concentration of sodium in the blood is thereby increased whereas that of potassium is decreased. There is a concomitant increase in the volume of blood and extracellular fluids, with a fall in hematocrit. It increases the rate of renal tubular absorption of sodium.
DTMA Absorption
No information avaliable
DTMA side effects and Toxicity
Symptoms of overdose include polyuria, polydipsia, increased blood volume, edema, and cardiac enlargement.
DTMA Patient Information
No information avaliable
DTMA Organisms Affected
Humans and other mammals
