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Pegvisomant Brand names, Pegvisomant Analogs

Pegvisomant Brand Names Mixture

  • No information avaliable

Pegvisomant Chemical_Formula


Pegvisomant RX_link

Pegvisomant fda sheet

Pegvisomant msds (material safety sheet)

Pegvisomant Synthesis Reference

No information avaliable

Pegvisomant Molecular Weight


Pegvisomant Melting Point

76 oC at pH 3.5 (Gomez-Orellana, I. et al., Protein Sci. 7:1352-1358 (1998).

Pegvisomant H2O Solubility

No information avaliable

Pegvisomant State


Pegvisomant LogP


Pegvisomant Dosage Forms

Solution (Subcutaneous Injection); Powder

Pegvisomant Indication

For treatment of acromegaly

Pegvisomant Pharmacology

Somavert is used for the treatment of acromegaly, which arises from excessive IGF-1 levels. Somavert selectively binds to growth hormone (GH) receptors on cell surfaces, where it blocks the binding of endogenous GH, and thus interferes with GH signal transduction. Inhibition of GH action results in decreased serum concentrations of insulin-like growth factor-I (IGF-I), and IGF binding protein-3 (IGFBP-3). This reduces the symptoms of acromegaly.

Pegvisomant Absorption

No information avaliable

Pegvisomant side effects and Toxicity

No information avaliable

Pegvisomant Patient Information


Pegvisomant Organisms Affected

Humans and other mammals