Somavert (Pfizer Inc)
Somavert (Pfizer Inc) Brand names, Somavert (Pfizer Inc) Analogs
Somavert (Pfizer Inc) Brand Names Mixture
- No information avaliable
Somavert (Pfizer Inc) Chemical_Formula
C990H1532N262O300S7
Somavert (Pfizer Inc) RX_link
http://www.rxlist.com/cgi/generic3/somavert.htm
Somavert (Pfizer Inc) fda sheet
Somavert (Pfizer Inc) msds (material safety sheet)
Somavert (Pfizer Inc) Synthesis Reference
No information avaliable
Somavert (Pfizer Inc) Molecular Weight
22129.0
Somavert (Pfizer Inc) Melting Point
76 oC at pH 3.5 (Gomez-Orellana, I. et al., Protein Sci. 7:1352-1358 (1998).
Somavert (Pfizer Inc) H2O Solubility
No information avaliable
Somavert (Pfizer Inc) State
Liquid
Somavert (Pfizer Inc) LogP
-0.411
Somavert (Pfizer Inc) Dosage Forms
Solution (Subcutaneous Injection); Powder
Somavert (Pfizer Inc) Indication
For treatment of acromegaly
Somavert (Pfizer Inc) Pharmacology
Somavert is used for the treatment of acromegaly, which arises from excessive IGF-1 levels. Somavert selectively binds to growth hormone (GH) receptors on cell surfaces, where it blocks the binding of endogenous GH, and thus interferes with GH signal transduction. Inhibition of GH action results in decreased serum concentrations of insulin-like growth factor-I (IGF-I), and IGF binding protein-3 (IGFBP-3). This reduces the symptoms of acromegaly.
Somavert (Pfizer Inc) Absorption
No information avaliable
Somavert (Pfizer Inc) side effects and Toxicity
No information avaliable
Somavert (Pfizer Inc) Patient Information
BIOD00044.html
Somavert (Pfizer Inc) Organisms Affected
Humans and other mammals
