Pantoloc
Brand names,
Pantoloc
Analogs
Pantoloc
Brand Names Mixture
Pantoloc
Chemical_Formula
C16H15F2N3O4S
Pantoloc
RX_link
http://www.rxlist.com/cgi/generic3/protonix.htm
Pantoloc
fda sheet
Pantoloc
msds (material safety sheet)
Pantoloc
Synthesis Reference
No information avaliable
Pantoloc
Molecular Weight
383.371 g/mol
Pantoloc
Melting Point
Because of gradual degradation of pantoprazole sodium during heating, the melting point cannot be determined.
Pantoloc
H2O Solubility
Freely soluble in water.
Pantoloc
State
Solid
Pantoloc
LogP
1.268
Pantoloc
Dosage Forms
Tablet (enteric-coated)
Pantoloc
Indication
Short-term (up to 16 weeks) treatment of erosive esophagitis.
Pantoloc
Pharmacology
Pantoprazole is a substituted benzimidazole indicated for the short-term treatment (up to 16 weeks) in the healing and symptomatic relief of erosive esophagitis. Pantoprazole is a proton pump inhibitor (PPI) that suppresses the final step in gastric acid production.
Pantoloc
Absorption
Pantoprazole is well absorbed; it undergoes little first-pass metabolism resulting in an absolute bioavailability of approximately 77%.
Pantoloc
side effects and Toxicity
No information avaliable
Pantoloc
Patient Information
Patients should be cautioned that PROTONIX Delayed-Release Tablets should not be split, crushed or chewed. The
tablets should be swallowed whole, with or without food in the stomach. Concomitant administration of antacids does
not affect the absorption of pantoprazole.
Pantoloc
Organisms Affected
Humans and other mammals