Protonix IV
Brand names,
Protonix IV
Analogs
Protonix IV
Brand Names Mixture
Protonix IV
Chemical_Formula
C16H15F2N3O4S
Protonix IV
RX_link
http://www.rxlist.com/cgi/generic3/protonix.htm
Protonix IV
fda sheet
Protonix IV
msds (material safety sheet)
Protonix IV
Synthesis Reference
No information avaliable
Protonix IV
Molecular Weight
383.371 g/mol
Protonix IV
Melting Point
Because of gradual degradation of pantoprazole sodium during heating, the melting point cannot be determined.
Protonix IV
H2O Solubility
Freely soluble in water.
Protonix IV
State
Solid
Protonix IV
LogP
1.268
Protonix IV
Dosage Forms
Tablet (enteric-coated)
Protonix IV
Indication
Short-term (up to 16 weeks) treatment of erosive esophagitis.
Protonix IV
Pharmacology
Pantoprazole is a substituted benzimidazole indicated for the short-term treatment (up to 16 weeks) in the healing and symptomatic relief of erosive esophagitis. Pantoprazole is a proton pump inhibitor (PPI) that suppresses the final step in gastric acid production.
Protonix IV
Absorption
Pantoprazole is well absorbed; it undergoes little first-pass metabolism resulting in an absolute bioavailability of approximately 77%.
Protonix IV
side effects and Toxicity
No information avaliable
Protonix IV
Patient Information
Patients should be cautioned that PROTONIX Delayed-Release Tablets should not be split, crushed or chewed. The
tablets should be swallowed whole, with or without food in the stomach. Concomitant administration of antacids does
not affect the absorption of pantoprazole.
Protonix IV
Organisms Affected
Humans and other mammals