Protonix
Brand names,
Protonix
Analogs
Protonix
Brand Names Mixture
Protonix
Chemical_Formula
C16H15F2N3O4S
Protonix
RX_link
http://www.rxlist.com/cgi/generic3/protonix.htm
Protonix
fda sheet
Protonix
msds (material safety sheet)
Protonix
Synthesis Reference
No information avaliable
Protonix
Molecular Weight
383.371 g/mol
Protonix
Melting Point
Because of gradual degradation of pantoprazole sodium during heating, the melting point cannot be determined.
Protonix
H2O Solubility
Freely soluble in water.
Protonix
State
Solid
Protonix
LogP
1.268
Protonix
Dosage Forms
Tablet (enteric-coated)
Protonix
Indication
Short-term (up to 16 weeks) treatment of erosive esophagitis.
Protonix
Pharmacology
Pantoprazole is a substituted benzimidazole indicated for the short-term treatment (up to 16 weeks) in the healing and symptomatic relief of erosive esophagitis. Pantoprazole is a proton pump inhibitor (PPI) that suppresses the final step in gastric acid production.
Protonix
Absorption
Pantoprazole is well absorbed; it undergoes little first-pass metabolism resulting in an absolute bioavailability of approximately 77%.
Protonix
side effects and Toxicity
No information avaliable
Protonix
Patient Information
Patients should be cautioned that PROTONIX Delayed-Release Tablets should not be split, crushed or chewed. The
tablets should be swallowed whole, with or without food in the stomach. Concomitant administration of antacids does
not affect the absorption of pantoprazole.
Protonix
Organisms Affected
Humans and other mammals