Pantoprazole Sodium
Brand names,
Pantoprazole Sodium
Analogs
Pantoprazole Sodium
Brand Names Mixture
Pantoprazole Sodium
Chemical_Formula
C16H15F2N3O4S
Pantoprazole Sodium
RX_link
http://www.rxlist.com/cgi/generic3/protonix.htm
Pantoprazole Sodium
fda sheet
Pantoprazole Sodium
msds (material safety sheet)
Pantoprazole Sodium
Synthesis Reference
No information avaliable
Pantoprazole Sodium
Molecular Weight
383.371 g/mol
Pantoprazole Sodium
Melting Point
Because of gradual degradation of pantoprazole sodium during heating, the melting point cannot be determined.
Pantoprazole Sodium
H2O Solubility
Freely soluble in water.
Pantoprazole Sodium
State
Solid
Pantoprazole Sodium
LogP
1.268
Pantoprazole Sodium
Dosage Forms
Tablet (enteric-coated)
Pantoprazole Sodium
Indication
Short-term (up to 16 weeks) treatment of erosive esophagitis.
Pantoprazole Sodium
Pharmacology
Pantoprazole is a substituted benzimidazole indicated for the short-term treatment (up to 16 weeks) in the healing and symptomatic relief of erosive esophagitis. Pantoprazole is a proton pump inhibitor (PPI) that suppresses the final step in gastric acid production.
Pantoprazole Sodium
Absorption
Pantoprazole is well absorbed; it undergoes little first-pass metabolism resulting in an absolute bioavailability of approximately 77%.
Pantoprazole Sodium
side effects and Toxicity
No information avaliable
Pantoprazole Sodium
Patient Information
Patients should be cautioned that PROTONIX Delayed-Release Tablets should not be split, crushed or chewed. The
tablets should be swallowed whole, with or without food in the stomach. Concomitant administration of antacids does
not affect the absorption of pantoprazole.
Pantoprazole Sodium
Organisms Affected
Humans and other mammals