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Mitotane Brand names, Mitotane Analogs

Mitotane Brand Names Mixture

  • No information avaliable

Mitotane Chemical_Formula


Mitotane RX_link

Mitotane fda sheet

Mitotane msds (material safety sheet)

Mitotane MSDS

Mitotane Synthesis Reference

No information avaliable

Mitotane Molecular Weight

320.04 g/mol

Mitotane Melting Point

77 oC

Mitotane H2O Solubility

0.1 mg/L

Mitotane State


Mitotane LogP


Mitotane Dosage Forms


Mitotane Indication

For treatment of inoperable adrenocortical tumours; Cushing's syndrome

Mitotane Pharmacology

Mitotane is an oral chemotherapeutic agent indicated in the treatment of inoperable adrenal cortical carcinoma of both functional and nonfunctional types. Mitotane can best be described as an adrenal cytotoxic agent, although it can cause adrenal inhibition, apparently without cellular destruction. The administration of Mitotane alters the extra-adrenal metabolism of cortisol in man; leading to a reduction in measurable 17-hydroxy corticosteroids, even though plasma levels of corticosteroids do not fall. The drug apparently causes increased formation of 6-B-hydroxyl cortisol.

Mitotane Absorption

About 40% oral Lysodren is absorbed

Mitotane side effects and Toxicity

No information avaliable

Mitotane Patient Information


Follow the links

Mitotane Organisms Affected

Humans and other mammals