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Mitotan Brand names, Mitotan Analogs

Mitotan Brand Names Mixture

  • No information avaliable

Mitotan Chemical_Formula


Mitotan RX_link

Mitotan fda sheet

Mitotan msds (material safety sheet)

Mitotan MSDS

Mitotan Synthesis Reference

No information avaliable

Mitotan Molecular Weight

320.04 g/mol

Mitotan Melting Point

77 oC

Mitotan H2O Solubility

0.1 mg/L

Mitotan State


Mitotan LogP


Mitotan Dosage Forms


Mitotan Indication

For treatment of inoperable adrenocortical tumours; Cushing's syndrome

Mitotan Pharmacology

Mitotane is an oral chemotherapeutic agent indicated in the treatment of inoperable adrenal cortical carcinoma of both functional and nonfunctional types. Mitotane can best be described as an adrenal cytotoxic agent, although it can cause adrenal inhibition, apparently without cellular destruction. The administration of Mitotane alters the extra-adrenal metabolism of cortisol in man; leading to a reduction in measurable 17-hydroxy corticosteroids, even though plasma levels of corticosteroids do not fall. The drug apparently causes increased formation of 6-B-hydroxyl cortisol.

Mitotan Absorption

About 40% oral Lysodren is absorbed

Mitotan side effects and Toxicity

No information avaliable

Mitotan Patient Information


Follow the links

Mitotan Organisms Affected

Humans and other mammals