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Methazolamide Brand names, Methazolamide Analogs

Methazolamide Brand Names Mixture

  • No information avaliable

Methazolamide Chemical_Formula


Methazolamide RX_link

Methazolamide fda sheet

Methazolamide msds (material safety sheet)

Methazolamide Synthesis Reference

Young, et al., J. Am. Chem. Soc. 78, 4649 (1956)

Methazolamide Molecular Weight

236.274 g/mol

Methazolamide Melting Point

213.5 oC

Methazolamide H2O Solubility

3500 mg/L

Methazolamide State


Methazolamide LogP


Methazolamide Dosage Forms


Methazolamide Indication

For treatment of chronic open-angle glaucoma and acute angle-closure glaucoma

Methazolamide Pharmacology

Methazolamide is topical carbonic anhydrase inhibitor. Methazolamide is indicated for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are insufficiently responsive to beta-blockers. Methazolamide is a sulfonamide derivative; however, it does not have any clinically significant antimicrobial properties. Although methazolamide achieves a high concentration in the cerebrospinal fluid, it is not-considered an effective anticonvulsant. Methazolamide has a weak and transient diuretic effect, therefore use results in an increase in urinary volume, with excretion of sodium, potassium and chloride.

Methazolamide Absorption

Methazolamide is well absorbed from the gastrointestinal tract.

Methazolamide side effects and Toxicity

Electrolyte imbalance, development of an acidotic state, and central nervous system effects might be expected to occur in the case of an overdose.

Methazolamide Patient Information

Methazolamide Organisms Affected

Humans and other mammals