MZM en es it fr

MZM Brand names, MZM Analogs

MZM Brand Names Mixture

  • No information avaliable

MZM Chemical_Formula

C5H8N4O3S2

MZM RX_link

http://www.rxlist.com/cgi/generic2/methaz.htm

MZM fda sheet

MZM msds (material safety sheet)

MZM Synthesis Reference

Young, et al., J. Am. Chem. Soc. 78, 4649 (1956)

MZM Molecular Weight

236.274 g/mol

MZM Melting Point

213.5 oC

MZM H2O Solubility

3500 mg/L

MZM State

Solid

MZM LogP

0.231

MZM Dosage Forms

Tablet

MZM Indication

For treatment of chronic open-angle glaucoma and acute angle-closure glaucoma

MZM Pharmacology

Methazolamide is topical carbonic anhydrase inhibitor. Methazolamide is indicated for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are insufficiently responsive to beta-blockers. Methazolamide is a sulfonamide derivative; however, it does not have any clinically significant antimicrobial properties. Although methazolamide achieves a high concentration in the cerebrospinal fluid, it is not-considered an effective anticonvulsant. Methazolamide has a weak and transient diuretic effect, therefore use results in an increase in urinary volume, with excretion of sodium, potassium and chloride.

MZM Absorption

Methazolamide is well absorbed from the gastrointestinal tract.

MZM side effects and Toxicity

Electrolyte imbalance, development of an acidotic state, and central nervous system effects might be expected to occur in the case of an overdose.

MZM Patient Information

MZM Organisms Affected

Humans and other mammals