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Methenamide Brand names, Methenamide Analogs

Methenamide Brand Names Mixture

  • No information avaliable

Methenamide Chemical_Formula


Methenamide RX_link

Methenamide fda sheet

Methenamide msds (material safety sheet)

Methenamide Synthesis Reference

Young, et al., J. Am. Chem. Soc. 78, 4649 (1956)

Methenamide Molecular Weight

236.274 g/mol

Methenamide Melting Point

213.5 oC

Methenamide H2O Solubility

3500 mg/L

Methenamide State


Methenamide LogP


Methenamide Dosage Forms


Methenamide Indication

For treatment of chronic open-angle glaucoma and acute angle-closure glaucoma

Methenamide Pharmacology

Methazolamide is topical carbonic anhydrase inhibitor. Methazolamide is indicated for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are insufficiently responsive to beta-blockers. Methazolamide is a sulfonamide derivative; however, it does not have any clinically significant antimicrobial properties. Although methazolamide achieves a high concentration in the cerebrospinal fluid, it is not-considered an effective anticonvulsant. Methazolamide has a weak and transient diuretic effect, therefore use results in an increase in urinary volume, with excretion of sodium, potassium and chloride.

Methenamide Absorption

Methazolamide is well absorbed from the gastrointestinal tract.

Methenamide side effects and Toxicity

Electrolyte imbalance, development of an acidotic state, and central nervous system effects might be expected to occur in the case of an overdose.

Methenamide Patient Information

Methenamide Organisms Affected

Humans and other mammals