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Neptazaneat Brand names, Neptazaneat Analogs

Neptazaneat Brand Names Mixture

  • No information avaliable

Neptazaneat Chemical_Formula

C5H8N4O3S2

Neptazaneat RX_link

http://www.rxlist.com/cgi/generic2/methaz.htm

Neptazaneat fda sheet

Neptazaneat msds (material safety sheet)

Neptazaneat Synthesis Reference

Young, et al., J. Am. Chem. Soc. 78, 4649 (1956)

Neptazaneat Molecular Weight

236.274 g/mol

Neptazaneat Melting Point

213.5 oC

Neptazaneat H2O Solubility

3500 mg/L

Neptazaneat State

Solid

Neptazaneat LogP

0.231

Neptazaneat Dosage Forms

Tablet

Neptazaneat Indication

For treatment of chronic open-angle glaucoma and acute angle-closure glaucoma

Neptazaneat Pharmacology

Methazolamide is topical carbonic anhydrase inhibitor. Methazolamide is indicated for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are insufficiently responsive to beta-blockers. Methazolamide is a sulfonamide derivative; however, it does not have any clinically significant antimicrobial properties. Although methazolamide achieves a high concentration in the cerebrospinal fluid, it is not-considered an effective anticonvulsant. Methazolamide has a weak and transient diuretic effect, therefore use results in an increase in urinary volume, with excretion of sodium, potassium and chloride.

Neptazaneat Absorption

Methazolamide is well absorbed from the gastrointestinal tract.

Neptazaneat side effects and Toxicity

Electrolyte imbalance, development of an acidotic state, and central nervous system effects might be expected to occur in the case of an overdose.

Neptazaneat Patient Information

Neptazaneat Organisms Affected

Humans and other mammals