Neptazaneat
Neptazaneat Brand names, Neptazaneat Analogs
Neptazaneat Brand Names Mixture
- No information avaliable
Neptazaneat Chemical_Formula
C5H8N4O3S2
Neptazaneat RX_link
http://www.rxlist.com/cgi/generic2/methaz.htm
Neptazaneat fda sheet
Neptazaneat msds (material safety sheet)
Neptazaneat Synthesis Reference
Young, et al., J. Am. Chem. Soc. 78, 4649 (1956)
Neptazaneat Molecular Weight
236.274 g/mol
Neptazaneat Melting Point
213.5 oC
Neptazaneat H2O Solubility
3500 mg/L
Neptazaneat State
Solid
Neptazaneat LogP
0.231
Neptazaneat Dosage Forms
Tablet
Neptazaneat Indication
For treatment of chronic open-angle glaucoma and acute angle-closure glaucoma
Neptazaneat Pharmacology
Methazolamide is topical carbonic anhydrase inhibitor. Methazolamide is indicated for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are insufficiently responsive to beta-blockers. Methazolamide is a sulfonamide derivative; however, it does not have any clinically significant antimicrobial properties. Although methazolamide achieves a high concentration in the cerebrospinal fluid, it is not-considered an effective anticonvulsant. Methazolamide has a weak and transient diuretic effect, therefore use results in an increase in urinary volume, with excretion of sodium, potassium and chloride.
Neptazaneat Absorption
Methazolamide is well absorbed from the gastrointestinal tract.
Neptazaneat side effects and Toxicity
Electrolyte imbalance, development of an acidotic state, and central nervous system effects might be expected to occur in the case of an overdose.
Neptazaneat Patient Information
Neptazaneat Organisms Affected
Humans and other mammals
