Neptazane
Neptazane Brand names, Neptazane Analogs
Neptazane Brand Names Mixture
- No information avaliable
Neptazane Chemical_Formula
C5H8N4O3S2
Neptazane RX_link
http://www.rxlist.com/cgi/generic2/methaz.htm
Neptazane fda sheet
Neptazane msds (material safety sheet)
Neptazane Synthesis Reference
Young, et al., J. Am. Chem. Soc. 78, 4649 (1956)
Neptazane Molecular Weight
236.274 g/mol
Neptazane Melting Point
213.5 oC
Neptazane H2O Solubility
3500 mg/L
Neptazane State
Solid
Neptazane LogP
0.231
Neptazane Dosage Forms
Tablet
Neptazane Indication
For treatment of chronic open-angle glaucoma and acute angle-closure glaucoma
Neptazane Pharmacology
Methazolamide is topical carbonic anhydrase inhibitor. Methazolamide is indicated for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are insufficiently responsive to beta-blockers. Methazolamide is a sulfonamide derivative; however, it does not have any clinically significant antimicrobial properties. Although methazolamide achieves a high concentration in the cerebrospinal fluid, it is not-considered an effective anticonvulsant. Methazolamide has a weak and transient diuretic effect, therefore use results in an increase in urinary volume, with excretion of sodium, potassium and chloride.
Neptazane Absorption
Methazolamide is well absorbed from the gastrointestinal tract.
Neptazane side effects and Toxicity
Electrolyte imbalance, development of an acidotic state, and central nervous system effects might be expected to occur in the case of an overdose.
Neptazane Patient Information
Neptazane Organisms Affected
Humans and other mammals
