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Neptazane Brand names, Neptazane Analogs

Neptazane Brand Names Mixture

  • No information avaliable

Neptazane Chemical_Formula

C5H8N4O3S2

Neptazane RX_link

http://www.rxlist.com/cgi/generic2/methaz.htm

Neptazane fda sheet

Neptazane msds (material safety sheet)

Neptazane Synthesis Reference

Young, et al., J. Am. Chem. Soc. 78, 4649 (1956)

Neptazane Molecular Weight

236.274 g/mol

Neptazane Melting Point

213.5 oC

Neptazane H2O Solubility

3500 mg/L

Neptazane State

Solid

Neptazane LogP

0.231

Neptazane Dosage Forms

Tablet

Neptazane Indication

For treatment of chronic open-angle glaucoma and acute angle-closure glaucoma

Neptazane Pharmacology

Methazolamide is topical carbonic anhydrase inhibitor. Methazolamide is indicated for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are insufficiently responsive to beta-blockers. Methazolamide is a sulfonamide derivative; however, it does not have any clinically significant antimicrobial properties. Although methazolamide achieves a high concentration in the cerebrospinal fluid, it is not-considered an effective anticonvulsant. Methazolamide has a weak and transient diuretic effect, therefore use results in an increase in urinary volume, with excretion of sodium, potassium and chloride.

Neptazane Absorption

Methazolamide is well absorbed from the gastrointestinal tract.

Neptazane side effects and Toxicity

Electrolyte imbalance, development of an acidotic state, and central nervous system effects might be expected to occur in the case of an overdose.

Neptazane Patient Information

Neptazane Organisms Affected

Humans and other mammals