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Naptazane Brand names, Naptazane Analogs

Naptazane Brand Names Mixture

  • No information avaliable

Naptazane Chemical_Formula


Naptazane RX_link

Naptazane fda sheet

Naptazane msds (material safety sheet)

Naptazane Synthesis Reference

Young, et al., J. Am. Chem. Soc. 78, 4649 (1956)

Naptazane Molecular Weight

236.274 g/mol

Naptazane Melting Point

213.5 oC

Naptazane H2O Solubility

3500 mg/L

Naptazane State


Naptazane LogP


Naptazane Dosage Forms


Naptazane Indication

For treatment of chronic open-angle glaucoma and acute angle-closure glaucoma

Naptazane Pharmacology

Methazolamide is topical carbonic anhydrase inhibitor. Methazolamide is indicated for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are insufficiently responsive to beta-blockers. Methazolamide is a sulfonamide derivative; however, it does not have any clinically significant antimicrobial properties. Although methazolamide achieves a high concentration in the cerebrospinal fluid, it is not-considered an effective anticonvulsant. Methazolamide has a weak and transient diuretic effect, therefore use results in an increase in urinary volume, with excretion of sodium, potassium and chloride.

Naptazane Absorption

Methazolamide is well absorbed from the gastrointestinal tract.

Naptazane side effects and Toxicity

Electrolyte imbalance, development of an acidotic state, and central nervous system effects might be expected to occur in the case of an overdose.

Naptazane Patient Information

Naptazane Organisms Affected

Humans and other mammals