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Mannitol Brand names, Mannitol Analogs

Mannitol Brand Names Mixture

  • No information avaliable

Mannitol Chemical_Formula


Mannitol RX_link

Mannitol fda sheet

Mannitol msds (material safety sheet)

Mannitol MSDS

Mannitol Synthesis Reference

No information avaliable

Mannitol Molecular Weight

182.172 g/mol

Mannitol Melting Point

168 oC

Mannitol H2O Solubility

216 mg/mL

Mannitol State


Mannitol LogP


Mannitol Dosage Forms

Liquid; Powder for solution; Solution

Mannitol Indication

Used for the promotion of diuresis before irreversible renal failure becomes established; The reduction of intracranial pressure, the treatment of cerebral edema, and the promotion of urinary excretion of toxic substances.

Mannitol Pharmacology

Chemically, mannitol is an alcohol and a sugar, or a polyol; it is similar to xylitol or sorbitol. However, mannitol has a tendency to lose a hydrogen ion in aqueous solutions, which causes the solution to become acidic. For this reason, it is not uncommon to add a substance to adjust its pH, such as sodium bicarbonate. Mannitol is commonly used to increase urine production (diuretic). It is also used to treat or prevent medical conditions that are caused by an increase in body fluids/water (e.g., cerebral edema, glaucoma, kidney failure). Mannitol is frequently given along with other diuretics (e.g., furosemide, chlorothiazide) and/or IV fluid replacement.

Mannitol Absorption

Approximately 7% of ingested mannitol is absorbed during gastrointestinal perfusion in uremic patients.

Mannitol side effects and Toxicity

LD50=1700 mg/kg (rat oral)

Mannitol Patient Information

Mannitol Organisms Affected

Humans and other mammals