Interleukin-1 receptor antagonist protein precursor
Interleukin-1 receptor antagonist protein precursor Brand names, Interleukin-1 receptor antagonist protein precursor Analogs
Interleukin-1 receptor antagonist protein precursor Brand Names Mixture
- No information avaliable
Interleukin-1 receptor antagonist protein precursor Chemical_Formula
C759H1186N208O232S10
Interleukin-1 receptor antagonist protein precursor RX_link
http://www.rxlist.com/cgi/generic/anakinra.htm
Interleukin-1 receptor antagonist protein precursor fda sheet
Interleukin-1 receptor antagonist protein precursor msds (material safety sheet)
Interleukin-1 receptor antagonist protein precursor Synthesis Reference
No information avaliable
Interleukin-1 receptor antagonist protein precursor Molecular Weight
17257.6
Interleukin-1 receptor antagonist protein precursor Melting Point
No information avaliable
Interleukin-1 receptor antagonist protein precursor H2O Solubility
No information avaliable
Interleukin-1 receptor antagonist protein precursor State
Liquid
Interleukin-1 receptor antagonist protein precursor LogP
-0.412
Interleukin-1 receptor antagonist protein precursor Dosage Forms
Solution
Interleukin-1 receptor antagonist protein precursor Indication
For treatment of adult rheumatoid arthritis
Interleukin-1 receptor antagonist protein precursor Pharmacology
Used to treat rheumatoid arthritis, Kineret blocks the biologic activity of IL-1 by competitively inhibiting IL-1 binding to the interleukin-1 type I receptor (IL-1RI), which is expressed in a wide variety of tissues and organs.1 IL-1 production is induced in response to inflammatory stimuli and mediates various physiologic responses including inflammatory and immunological responses. Patients with rheumatoid arthritis have elevated levels of IL-1. The levels of the naturally occurring IL-1Ra in synovium and synovial fluid from rheumatoid arthritis (RA) patients are not sufficient to compete with the elevated amount of locally produced IL-1. Increasing the levels of IL-1Ra by artificial means reduces the negative effects (cartilage degradation, bone resorption) of IL-1.
Interleukin-1 receptor antagonist protein precursor Absorption
No information avaliable
Interleukin-1 receptor antagonist protein precursor side effects and Toxicity
No information avaliable
Interleukin-1 receptor antagonist protein precursor Patient Information
BIOD00060.html
Interleukin-1 receptor antagonist protein precursor Organisms Affected
Humans and other mammals
