IL1 inhibitor
IL1 inhibitor Brand names, IL1 inhibitor Analogs
IL1 inhibitor Brand Names Mixture
- No information avaliable
IL1 inhibitor Chemical_Formula
C759H1186N208O232S10
IL1 inhibitor RX_link
http://www.rxlist.com/cgi/generic/anakinra.htm
IL1 inhibitor fda sheet
IL1 inhibitor msds (material safety sheet)
IL1 inhibitor Synthesis Reference
No information avaliable
IL1 inhibitor Molecular Weight
17257.6
IL1 inhibitor Melting Point
No information avaliable
IL1 inhibitor H2O Solubility
No information avaliable
IL1 inhibitor State
Liquid
IL1 inhibitor LogP
-0.412
IL1 inhibitor Dosage Forms
Solution
IL1 inhibitor Indication
For treatment of adult rheumatoid arthritis
IL1 inhibitor Pharmacology
Used to treat rheumatoid arthritis, Kineret blocks the biologic activity of IL-1 by competitively inhibiting IL-1 binding to the interleukin-1 type I receptor (IL-1RI), which is expressed in a wide variety of tissues and organs.1 IL-1 production is induced in response to inflammatory stimuli and mediates various physiologic responses including inflammatory and immunological responses. Patients with rheumatoid arthritis have elevated levels of IL-1. The levels of the naturally occurring IL-1Ra in synovium and synovial fluid from rheumatoid arthritis (RA) patients are not sufficient to compete with the elevated amount of locally produced IL-1. Increasing the levels of IL-1Ra by artificial means reduces the negative effects (cartilage degradation, bone resorption) of IL-1.
IL1 inhibitor Absorption
No information avaliable
IL1 inhibitor side effects and Toxicity
No information avaliable
IL1 inhibitor Patient Information
BIOD00060.html
IL1 inhibitor Organisms Affected
Humans and other mammals
