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IL-1ra Brand names, IL-1ra Analogs

IL-1ra Brand Names Mixture

  • No information avaliable

IL-1ra Chemical_Formula


IL-1ra RX_link

IL-1ra fda sheet

IL-1ra msds (material safety sheet)

IL-1ra Synthesis Reference

No information avaliable

IL-1ra Molecular Weight


IL-1ra Melting Point

No information avaliable

IL-1ra H2O Solubility

No information avaliable

IL-1ra State


IL-1ra LogP


IL-1ra Dosage Forms


IL-1ra Indication

For treatment of adult rheumatoid arthritis

IL-1ra Pharmacology

Used to treat rheumatoid arthritis, Kineret blocks the biologic activity of IL-1 by competitively inhibiting IL-1 binding to the interleukin-1 type I receptor (IL-1RI), which is expressed in a wide variety of tissues and organs.1 IL-1 production is induced in response to inflammatory stimuli and mediates various physiologic responses including inflammatory and immunological responses. Patients with rheumatoid arthritis have elevated levels of IL-1. The levels of the naturally occurring IL-1Ra in synovium and synovial fluid from rheumatoid arthritis (RA) patients are not sufficient to compete with the elevated amount of locally produced IL-1. Increasing the levels of IL-1Ra by artificial means reduces the negative effects (cartilage degradation, bone resorption) of IL-1.

IL-1ra Absorption

No information avaliable

IL-1ra side effects and Toxicity

No information avaliable

IL-1ra Patient Information


IL-1ra Organisms Affected

Humans and other mammals