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IL-1RN Brand names, IL-1RN Analogs

IL-1RN Brand Names Mixture

  • No information avaliable

IL-1RN Chemical_Formula


IL-1RN RX_link

IL-1RN fda sheet

IL-1RN msds (material safety sheet)

IL-1RN Synthesis Reference

No information avaliable

IL-1RN Molecular Weight


IL-1RN Melting Point

No information avaliable

IL-1RN H2O Solubility

No information avaliable

IL-1RN State




IL-1RN Dosage Forms


IL-1RN Indication

For treatment of adult rheumatoid arthritis

IL-1RN Pharmacology

Used to treat rheumatoid arthritis, Kineret blocks the biologic activity of IL-1 by competitively inhibiting IL-1 binding to the interleukin-1 type I receptor (IL-1RI), which is expressed in a wide variety of tissues and organs.1 IL-1 production is induced in response to inflammatory stimuli and mediates various physiologic responses including inflammatory and immunological responses. Patients with rheumatoid arthritis have elevated levels of IL-1. The levels of the naturally occurring IL-1Ra in synovium and synovial fluid from rheumatoid arthritis (RA) patients are not sufficient to compete with the elevated amount of locally produced IL-1. Increasing the levels of IL-1Ra by artificial means reduces the negative effects (cartilage degradation, bone resorption) of IL-1.

IL-1RN Absorption

No information avaliable

IL-1RN side effects and Toxicity

No information avaliable

IL-1RN Patient Information


IL-1RN Organisms Affected

Humans and other mammals