PharmacyCodes



Idarubicinum [Inn-Latin] en es it fr

Idarubicinum [Inn-Latin] Brand names, Idarubicinum [Inn-Latin] Analogs

Idarubicinum [Inn-Latin] Brand Names Mixture

  • No information avaliable

Idarubicinum [Inn-Latin] Chemical_Formula

C26H27NO9

Idarubicinum [Inn-Latin] RX_link

http://www.rxlist.com/cgi/generic2/idarubicin.htm

Idarubicinum [Inn-Latin] fda sheet

Idarubicinum_[Inn-Latin] FDA

Idarubicinum [Inn-Latin] msds (material safety sheet)

Idarubicinum [Inn-Latin] Synthesis Reference

No information avaliable

Idarubicinum [Inn-Latin] Molecular Weight

497.494 g/mol

Idarubicinum [Inn-Latin] Melting Point

No information avaliable

Idarubicinum [Inn-Latin] H2O Solubility

No information avaliable

Idarubicinum [Inn-Latin] State

Solid

Idarubicinum [Inn-Latin] LogP

0.803

Idarubicinum [Inn-Latin] Dosage Forms

Powder for solution

Idarubicinum [Inn-Latin] Indication

For the treatment of acute myeloid leukemia (AML) in adults. This includes French-American-British (FAB) classifications M1 through M7.

Idarubicinum [Inn-Latin] Pharmacology

Idarubicin is an antineoplastic in the anthracycline class. General properties of drugs in this class include: interaction with DNA in a variety of different ways including intercalation (squeezing between the base pairs), DNA strand breakage and inhibition with the enzyme topoisomerase II. Most of these compounds have been isolated from natural sources and antibiotics. However, they lack the specificity of the antimicrobial antibiotics and thus produce significant toxicity. The anthracyclines are among the most important antitumor drugs available. Doxorubicin is widely used for the treatment of several solid tumors while daunorubicin and idarubicin are used exclusively for the treatment of leukemia. Idarubicin may also inhibit polymerase activity, affect regulation of gene expression, and produce free radical damage to DNA. Idarubicin possesses an antitumor effect against a wide spectrum of tumors, either grafted or spontaneous. The anthracyclines are cell cycle-nonspecific.

Idarubicinum [Inn-Latin] Absorption

No information avaliable

Idarubicinum [Inn-Latin] side effects and Toxicity

No information avaliable

Idarubicinum [Inn-Latin] Patient Information

No information avaliable

Idarubicinum [Inn-Latin] Organisms Affected

Humans, other mammals and bacteria