PharmacyCodes



Idarubicin Hcl en es it fr

Idarubicin Hcl Brand names, Idarubicin Hcl Analogs

Idarubicin Hcl Brand Names Mixture

  • No information avaliable

Idarubicin Hcl Chemical_Formula

C26H27NO9

Idarubicin Hcl RX_link

http://www.rxlist.com/cgi/generic2/idarubicin.htm

Idarubicin Hcl fda sheet

Idarubicin_Hcl FDA

Idarubicin Hcl msds (material safety sheet)

Idarubicin Hcl Synthesis Reference

No information avaliable

Idarubicin Hcl Molecular Weight

497.494 g/mol

Idarubicin Hcl Melting Point

No information avaliable

Idarubicin Hcl H2O Solubility

No information avaliable

Idarubicin Hcl State

Solid

Idarubicin Hcl LogP

0.803

Idarubicin Hcl Dosage Forms

Powder for solution

Idarubicin Hcl Indication

For the treatment of acute myeloid leukemia (AML) in adults. This includes French-American-British (FAB) classifications M1 through M7.

Idarubicin Hcl Pharmacology

Idarubicin is an antineoplastic in the anthracycline class. General properties of drugs in this class include: interaction with DNA in a variety of different ways including intercalation (squeezing between the base pairs), DNA strand breakage and inhibition with the enzyme topoisomerase II. Most of these compounds have been isolated from natural sources and antibiotics. However, they lack the specificity of the antimicrobial antibiotics and thus produce significant toxicity. The anthracyclines are among the most important antitumor drugs available. Doxorubicin is widely used for the treatment of several solid tumors while daunorubicin and idarubicin are used exclusively for the treatment of leukemia. Idarubicin may also inhibit polymerase activity, affect regulation of gene expression, and produce free radical damage to DNA. Idarubicin possesses an antitumor effect against a wide spectrum of tumors, either grafted or spontaneous. The anthracyclines are cell cycle-nonspecific.

Idarubicin Hcl Absorption

No information avaliable

Idarubicin Hcl side effects and Toxicity

No information avaliable

Idarubicin Hcl Patient Information

No information avaliable

Idarubicin Hcl Organisms Affected

Humans, other mammals and bacteria