Idarubicin Hcl Pfs en es it fr

Idarubicin Hcl Pfs Brand names, Idarubicin Hcl Pfs Analogs

Idarubicin Hcl Pfs Brand Names Mixture

  • No information avaliable

Idarubicin Hcl Pfs Chemical_Formula

C26H27NO9

Idarubicin Hcl Pfs RX_link

http://www.rxlist.com/cgi/generic2/idarubicin.htm

Idarubicin Hcl Pfs fda sheet

Idarubicin_Hcl_Pfs FDA

Idarubicin Hcl Pfs msds (material safety sheet)

Idarubicin Hcl Pfs Synthesis Reference

No information avaliable

Idarubicin Hcl Pfs Molecular Weight

497.494 g/mol

Idarubicin Hcl Pfs Melting Point

No information avaliable

Idarubicin Hcl Pfs H2O Solubility

No information avaliable

Idarubicin Hcl Pfs State

Solid

Idarubicin Hcl Pfs LogP

0.803

Idarubicin Hcl Pfs Dosage Forms

Powder for solution

Idarubicin Hcl Pfs Indication

For the treatment of acute myeloid leukemia (AML) in adults. This includes French-American-British (FAB) classifications M1 through M7.

Idarubicin Hcl Pfs Pharmacology

Idarubicin is an antineoplastic in the anthracycline class. General properties of drugs in this class include: interaction with DNA in a variety of different ways including intercalation (squeezing between the base pairs), DNA strand breakage and inhibition with the enzyme topoisomerase II. Most of these compounds have been isolated from natural sources and antibiotics. However, they lack the specificity of the antimicrobial antibiotics and thus produce significant toxicity. The anthracyclines are among the most important antitumor drugs available. Doxorubicin is widely used for the treatment of several solid tumors while daunorubicin and idarubicin are used exclusively for the treatment of leukemia. Idarubicin may also inhibit polymerase activity, affect regulation of gene expression, and produce free radical damage to DNA. Idarubicin possesses an antitumor effect against a wide spectrum of tumors, either grafted or spontaneous. The anthracyclines are cell cycle-nonspecific.

Idarubicin Hcl Pfs Absorption

No information avaliable

Idarubicin Hcl Pfs side effects and Toxicity

No information avaliable

Idarubicin Hcl Pfs Patient Information

No information avaliable

Idarubicin Hcl Pfs Organisms Affected

Humans, other mammals and bacteria