Idamycin Pfs
Idamycin Pfs Brand names, Idamycin Pfs Analogs
Idamycin Pfs Brand Names Mixture
- No information avaliable
Idamycin Pfs Chemical_Formula
C26H27NO9
Idamycin Pfs RX_link
http://www.rxlist.com/cgi/generic2/idarubicin.htm
Idamycin Pfs fda sheet
Idamycin Pfs msds (material safety sheet)
Idamycin Pfs Synthesis Reference
No information avaliable
Idamycin Pfs Molecular Weight
497.494 g/mol
Idamycin Pfs Melting Point
No information avaliable
Idamycin Pfs H2O Solubility
No information avaliable
Idamycin Pfs State
Solid
Idamycin Pfs LogP
0.803
Idamycin Pfs Dosage Forms
Powder for solution
Idamycin Pfs Indication
For the treatment of acute myeloid leukemia (AML) in adults. This includes French-American-British (FAB) classifications M1 through M7.
Idamycin Pfs Pharmacology
Idarubicin is an antineoplastic in the anthracycline class. General properties of drugs in this class include: interaction with DNA in a variety of different ways including intercalation (squeezing between the base pairs), DNA strand breakage and inhibition with the enzyme topoisomerase II. Most of these compounds have been isolated from natural sources and antibiotics. However, they lack the specificity of the antimicrobial antibiotics and thus produce significant toxicity. The anthracyclines are among the most important antitumor drugs available. Doxorubicin is widely used for the treatment of several solid tumors while daunorubicin and idarubicin are used exclusively for the treatment of leukemia. Idarubicin may also inhibit polymerase activity, affect regulation of gene expression, and produce free radical damage to DNA. Idarubicin possesses an antitumor effect against a wide spectrum of tumors, either grafted or spontaneous. The anthracyclines are cell cycle-nonspecific.
Idamycin Pfs Absorption
No information avaliable
Idamycin Pfs side effects and Toxicity
No information avaliable
Idamycin Pfs Patient Information
No information avaliable
Idamycin Pfs Organisms Affected
Humans, other mammals and bacteria
