Granisetron
Brand names,
Granisetron
Analogs
Granisetron
Brand Names Mixture
- Tarka (Trandolapril + Verapamil hydrochloride)
Granisetron
Chemical_Formula
C18H24N4O
Granisetron
RX_link
http://www.rxlist.com/cgi/generic/granisetron.htm
Granisetron
fda sheet
Granisetron
msds (material safety sheet)
Granisetron
Synthesis Reference
No information avaliable
Granisetron
Molecular Weight
312.41 g/mol
Granisetron
Melting Point
219 oC (HCl salt)
Granisetron
H2O Solubility
No information avaliable
Granisetron
State
Solid
Granisetron
LogP
2.795
Granisetron
Dosage Forms
Liquid; Tablet
Granisetron
Indication
For the prevention of: nausea and vomiting associated with initial and repeat courses of emetogenic cancer therapy, including high-dose cisplatin.
Granisetron
Pharmacology
No information avaliable
Granisetron
Absorption
Absorption of is rapid and complete, though oral bioavailability is reduced to about 60% as a result of first pass metabolism.
Granisetron
side effects and Toxicity
LD50>2000 mg/kg (rat, oral)
Granisetron
Patient Information
Granisetron
Organisms Affected
Humans and other mammals