Granisetron hydrochloride and intermediates
Brand names,
Granisetron hydrochloride and intermediates
Analogs
Granisetron hydrochloride and intermediates
Brand Names Mixture
- Tarka (Trandolapril + Verapamil hydrochloride)
Granisetron hydrochloride and intermediates
Chemical_Formula
C18H24N4O
Granisetron hydrochloride and intermediates
RX_link
http://www.rxlist.com/cgi/generic/granisetron.htm
Granisetron hydrochloride and intermediates
fda sheet
Granisetron hydrochloride and intermediates
msds (material safety sheet)
Granisetron hydrochloride and intermediates
Synthesis Reference
No information avaliable
Granisetron hydrochloride and intermediates
Molecular Weight
312.41 g/mol
Granisetron hydrochloride and intermediates
Melting Point
219 oC (HCl salt)
Granisetron hydrochloride and intermediates
H2O Solubility
No information avaliable
Granisetron hydrochloride and intermediates
State
Solid
Granisetron hydrochloride and intermediates
LogP
2.795
Granisetron hydrochloride and intermediates
Dosage Forms
Liquid; Tablet
Granisetron hydrochloride and intermediates
Indication
For the prevention of: nausea and vomiting associated with initial and repeat courses of emetogenic cancer therapy, including high-dose cisplatin.
Granisetron hydrochloride and intermediates
Pharmacology
No information avaliable
Granisetron hydrochloride and intermediates
Absorption
Absorption of is rapid and complete, though oral bioavailability is reduced to about 60% as a result of first pass metabolism.
Granisetron hydrochloride and intermediates
side effects and Toxicity
LD50>2000 mg/kg (rat, oral)
Granisetron hydrochloride and intermediates
Patient Information
Granisetron hydrochloride and intermediates
Organisms Affected
Humans and other mammals