Granisetron HCl
Brand names,
Granisetron HCl
Analogs
Granisetron HCl
Brand Names Mixture
- Tarka (Trandolapril + Verapamil hydrochloride)
Granisetron HCl
Chemical_Formula
C18H24N4O
Granisetron HCl
RX_link
http://www.rxlist.com/cgi/generic/granisetron.htm
Granisetron HCl
fda sheet
Granisetron HCl
msds (material safety sheet)
Granisetron HCl
Synthesis Reference
No information avaliable
Granisetron HCl
Molecular Weight
312.41 g/mol
Granisetron HCl
Melting Point
219 oC (HCl salt)
Granisetron HCl
H2O Solubility
No information avaliable
Granisetron HCl
State
Solid
Granisetron HCl
LogP
2.795
Granisetron HCl
Dosage Forms
Liquid; Tablet
Granisetron HCl
Indication
For the prevention of: nausea and vomiting associated with initial and repeat courses of emetogenic cancer therapy, including high-dose cisplatin.
Granisetron HCl
Pharmacology
No information avaliable
Granisetron HCl
Absorption
Absorption of is rapid and complete, though oral bioavailability is reduced to about 60% as a result of first pass metabolism.
Granisetron HCl
side effects and Toxicity
LD50>2000 mg/kg (rat, oral)
Granisetron HCl
Patient Information
Granisetron HCl
Organisms Affected
Humans and other mammals