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Brand names,
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Analogs
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Brand Names Mixture
- Tarka (Trandolapril + Verapamil hydrochloride)
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Chemical_Formula
C18H24N4O
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RX_link
http://www.rxlist.com/cgi/generic/granisetron.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
312.41 g/mol
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Melting Point
219 oC (HCl salt)
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H2O Solubility
No information avaliable
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State
Solid
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LogP
2.795
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Dosage Forms
Liquid; Tablet
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Indication
For the prevention of: nausea and vomiting associated with initial and repeat courses of emetogenic cancer therapy, including high-dose cisplatin.
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Pharmacology
No information avaliable
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Absorption
Absorption of is rapid and complete, though oral bioavailability is reduced to about 60% as a result of first pass metabolism.
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side effects and Toxicity
LD50>2000 mg/kg (rat, oral)
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Patient Information
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Organisms Affected
Humans and other mammals