Fludarabine

Fludarabine Brand names, Fludarabine Analogs

Fludarabine Brand Names Mixture

No information avaliable

Fludarabine Chemical_Formula

C₁₀H₁₃FN₅O₇P

Fludarabine RX_link

http://www.rxlist.com/cgi/generic/fludarabine.htm

Fludarabine fda sheet

Fludarabine FDA

Fludarabine msds (material safety sheet)

Fludarabine MSDS

Fludarabine Synthesis Reference

J. A. Montgomery, U.S. pat. 4,210,745 (1980 to U.S. Dept. Health, Education and Welfare)

Fludarabine Molecular Weight

365.212 g/mol

Fludarabine Melting Point

260 ^oC

Fludarabine H₂O Solubility

3.53 mg/ml

Fludarabine State

Solid

Fludarabine LogP

-0.852

Fludarabine Dosage Forms

Tablet; Powder for solution; IV solution

Fludarabine Indication

For the treatment of adult patients with B-cell chronic lymphocytic leukemia (CLL) who have not responded to or whose disease has progressed during treatment with at least one standard alkylating-agent containing regimen

Fludarabine Pharmacology

Fludarabine is a chemotherapy drug used in the treatment of chronic lymphocytic leukemia. It acts at DNA polymerase alpha, ribonucleotide reductase and DNA primase, results in the inhibition of DNA synthesis, and destroys the cancer cells.

Fludarabine Absorption

No information avaliable

Fludarabine side effects and Toxicity