FAMP
Brand names,
FAMP
Analogs
FAMP
Brand Names Mixture
FAMP
Chemical_Formula
C10H13FN5O7P
FAMP
RX_link
http://www.rxlist.com/cgi/generic/fludarabine.htm
FAMP
fda sheet
FAMP
msds (material safety sheet)
FAMP
Synthesis Reference
J. A. Montgomery, U.S. pat. 4,210,745 (1980 to U.S. Dept. Health, Education and Welfare)
FAMP
Molecular Weight
365.212 g/mol
FAMP
Melting Point
260 oC
FAMP
H2O Solubility
3.53 mg/ml
FAMP
State
Solid
FAMP
LogP
-0.852
FAMP
Dosage Forms
Tablet; Powder for solution; IV solution
FAMP
Indication
For the treatment of adult patients with B-cell chronic lymphocytic leukemia (CLL) who have not responded to or whose disease has progressed during treatment with at least one standard alkylating-agent containing regimen
FAMP
Pharmacology
Fludarabine is a chemotherapy drug used in the treatment of chronic lymphocytic leukemia. It acts at DNA polymerase alpha, ribonucleotide reductase and DNA primase, results in the inhibition of DNA synthesis, and destroys the cancer cells.
FAMP
Absorption
No information avaliable
FAMP
side effects and Toxicity
No information avaliable
FAMP
Patient Information
FAMP
Organisms Affected
Humans and other mammals