Fludara
Fludara Brand names, Fludara Analogs
Fludara Brand Names Mixture
- No information avaliable
Fludara Chemical_Formula
C10H13FN5O7P
Fludara RX_link
http://www.rxlist.com/cgi/generic/fludarabine.htm
Fludara fda sheet
Fludara msds (material safety sheet)
Fludara Synthesis Reference
J. A. Montgomery, U.S. pat. 4,210,745 (1980 to U.S. Dept. Health, Education and Welfare)
Fludara Molecular Weight
365.212 g/mol
Fludara Melting Point
260 oC
Fludara H2O Solubility
3.53 mg/ml
Fludara State
Solid
Fludara LogP
-0.852
Fludara Dosage Forms
Tablet; Powder for solution; IV solution
Fludara Indication
For the treatment of adult patients with B-cell chronic lymphocytic leukemia (CLL) who have not responded to or whose disease has progressed during treatment with at least one standard alkylating-agent containing regimen
Fludara Pharmacology
Fludarabine is a chemotherapy drug used in the treatment of chronic lymphocytic leukemia. It acts at DNA polymerase alpha, ribonucleotide reductase and DNA primase, results in the inhibition of DNA synthesis, and destroys the cancer cells.
Fludara Absorption
No information avaliable
Fludara side effects and Toxicity
No information avaliable
Fludara Patient Information
Fludara Organisms Affected
Humans and other mammals
