Finasteride
Finasteride Brand names, Finasteride Analogs
Finasteride Brand Names Mixture
- No information avaliable
Finasteride Chemical_Formula
C23H36N2O2
Finasteride RX_link
http://www.rxlist.com/cgi/generic3/propecia.htm
Finasteride fda sheet
Finasteride msds (material safety sheet)
Finasteride Synthesis Reference
No information avaliable
Finasteride Molecular Weight
372.544 g/mol
Finasteride Melting Point
252-254 oC
Finasteride H2O Solubility
11.7 mg/L
Finasteride State
Solid
Finasteride LogP
4.277
Finasteride Dosage Forms
Tablet
Finasteride Indication
For the treatment of symptomatic benign prostatic hyperplasia (BPH) in men with an enlarged prostate to: Improve symptoms, reduce the risk of acute urinary retention, reduce the risk of the need for surgery including transurethral resection of the prostat.
Finasteride Pharmacology
Finasteride is indicated for the treatment of male pattern hair loss (androgenetic alopecia) in men only. Finasteride is a competitive and specific inhibitor of Type II 5a-reductase, an intracellular enzyme that converts the androgen testosterone into DHT. Two distinct isozymes are found in mice, rats, monkeys, and humans: Type I and II. Each of these isozymes is differentially expressed in tissues and developmental stages. In humans, Type I 5a-reductase is predominant in the sebaceous glands of most regions of skin, including scalp, and liver. Type I 5a-reductase is responsible for approximately one-third of circulating DHT. The Type II 5a-reductase isozyme is primarily found in prostate, seminal vesicles, epididymides, and hair follicles as well as liver, and is responsible for two-thirds of circulating DHT.
Finasteride Absorption
No information avaliable
Finasteride side effects and Toxicity
No information avaliable
Finasteride Patient Information
No information avaliable
Finasteride Organisms Affected
Humans and other mammals
