Proscar
Brand names,
Proscar
Analogs
Proscar
Brand Names Mixture
Proscar
Chemical_Formula
C23H36N2O2
Proscar
RX_link
http://www.rxlist.com/cgi/generic3/propecia.htm
Proscar
fda sheet
Proscar
msds (material safety sheet)
Proscar
Synthesis Reference
No information avaliable
Proscar
Molecular Weight
372.544 g/mol
Proscar
Melting Point
252-254 oC
Proscar
H2O Solubility
11.7 mg/L
Proscar
State
Solid
Proscar
LogP
4.277
Proscar
Dosage Forms
Tablet
Proscar
Indication
For the treatment of symptomatic benign prostatic hyperplasia (BPH) in men with an enlarged prostate to: Improve symptoms, reduce the risk of acute urinary retention, reduce the risk of the need for surgery including transurethral resection of the prostat.
Proscar
Pharmacology
Finasteride is indicated for the treatment of male pattern hair loss (androgenetic alopecia) in men only. Finasteride is a competitive and specific inhibitor of Type II 5a-reductase, an intracellular enzyme that converts the androgen testosterone into DHT. Two distinct isozymes are found in mice, rats, monkeys, and humans: Type I and II. Each of these isozymes is differentially expressed in tissues and developmental stages. In humans, Type I 5a-reductase is predominant in the sebaceous glands of most regions of skin, including scalp, and liver. Type I 5a-reductase is responsible for approximately one-third of circulating DHT. The Type II 5a-reductase isozyme is primarily found in prostate, seminal vesicles, epididymides, and hair follicles as well as liver, and is responsible for two-thirds of circulating DHT.
Proscar
Absorption
No information avaliable
Proscar
side effects and Toxicity
No information avaliable
Proscar
Patient Information
No information avaliable
Proscar
Organisms Affected
Humans and other mammals