PharmacyCodes



Fenantoin Mn Pharma en es it fr

Fenantoin Mn Pharma Brand names, Fenantoin Mn Pharma Analogs

Fenantoin Mn Pharma Brand Names Mixture

  • Dilantin W Phenobarbital 15mg (Phenobarbital + Phenytoin Sodium)
  • Dilantin W Phenobarbital 30mg Cap (Phenobarbital + Phenytoin Sodium)

Fenantoin Mn Pharma Chemical_Formula

C15H12N2O2

Fenantoin Mn Pharma RX_link

http://www.rxlist.com/cgi/generic/phenyt.htm

Fenantoin Mn Pharma fda sheet

Fenantoin_Mn_Pharma FDA

Fenantoin Mn Pharma msds (material safety sheet)

Fenantoin_Mn_Pharma MSDS

Fenantoin Mn Pharma Synthesis Reference

Henze, U.S. Pat. 2,409,754 (1946)

Fenantoin Mn Pharma Molecular Weight

252.268 g/mol

Fenantoin Mn Pharma Melting Point

286 oC

Fenantoin Mn Pharma H2O Solubility

32 mg/L

Fenantoin Mn Pharma State

Solid

Fenantoin Mn Pharma LogP

2.241

Fenantoin Mn Pharma Dosage Forms

Capsule (extended release); Liquid; Solution; Suspension; Tablet

Fenantoin Mn Pharma Indication

For the control of generalized tonic-clonic (grand mal) and complex partial (psychomotor, temporal lobe) seizures and prevention and treatment of seizures occurring during or following neurosurgery.

Fenantoin Mn Pharma Pharmacology

Phenytoin is an antiepileptic drug which can be useful in the treatment of epilepsy. The primary site of action appears to be the motor cortex where spread of seizure activity is inhibited. Phenytoin reduces the maximal activity of brain stem centers responsible for the tonic phase of tonic-clonic (grand mal) seizures. Phenytoin acts to damp the unwanted, runaway brain activity seen in seizure by reducing electrical conductance among brain cells. It lacks the sedation effects associated with phenobarbital. There are some indications that phenytoin has other effects, including anxiety control and mood stabilization, although it has never been approved for those purposes by the FDA.

Fenantoin Mn Pharma Absorption

Bioavailability 70-100% oral, 24.4% for rectal and intravenous administration. Rapid rate of absorption with peak blood concentration expected in 1½ to 3 hours.

Fenantoin Mn Pharma side effects and Toxicity

Oral, mouse: LD50 = 150 mg/kg; Oral, rat: LD50 = 1635 mg/kg. Symptoms of overdose include coma, difficulty in pronouncing words correctly, involuntary eye movement, lack of muscle coordination, low blood pressure, nausea, sluggishness, slurred speech, tremors, and vomiting.

Fenantoin Mn Pharma Patient Information

Patients taking phenytoin should be advised of the importance of adhering strictly to the prescribed dosage regimen, and of informing the physician of any clinical condition in which it is not possible to take the drug orally as prescribed, eg, surgery, etc.

Patients should also be cautioned on the use of other drugs or alcoholic beverages without first seeking the physician's advice.

Patients should be instructed to call their physician if skin rash develops.

The importance of good dental hygiene should be stressed in order to minimize the development of gingival hyperplasia and its complications.

Do not use capsules which are discolored.

Fenantoin Mn Pharma Organisms Affected

Humans and other mammals