EM
EM Brand names, EM Analogs
EM Brand Names Mixture
- No information avaliable
EM Chemical_Formula
C18H22N2
EM RX_link
No information avaliable
EM fda sheet
EM msds (material safety sheet)
EM Synthesis Reference
No information avaliable
EM Molecular Weight
266.381 g/mol
EM Melting Point
No information avaliable
EM H2O Solubility
No information avaliable
EM State
Solid
EM LogP
3.338
EM Dosage Forms
Liquid
EM Indication
For prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness, and vertigo (dizziness caused by other medical problems).
EM Pharmacology
Cyclizine is a piperazine-derivative antihistamine used as an antivertigo/antiemetic agent. Cyclizine is used in the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness. Additionally, it has been used in the management of vertigo in diseases affecting the vestibular apparatus. Although the mechanism by which cyclizine exerts its antiemetic and antivertigo effects has not been fully elucidated, its central anticholinergic properties are partially responsible. The drug depresses labyrinth excitability and vestibular stimulation, and it may affect the medullary chemoreceptor trigger zone. It also possesses anticholinergic, antihistaminic, central nervous system depressant, and local anesthetic effects.
EM Absorption
No information avaliable
EM side effects and Toxicity
No information avaliable
EM Patient Information
No information avaliable
EM Organisms Affected
Humans and other mammals
