Marezine
Brand names,
Marezine
Analogs
Marezine
Brand Names Mixture
Marezine
Chemical_Formula
C18H22N2
Marezine
RX_link
No information avaliable
Marezine
fda sheet
Marezine
msds (material safety sheet)
Marezine
Synthesis Reference
No information avaliable
Marezine
Molecular Weight
266.381 g/mol
Marezine
Melting Point
No information avaliable
Marezine
H2O Solubility
No information avaliable
Marezine
State
Solid
Marezine
LogP
3.338
Marezine
Dosage Forms
Liquid
Marezine
Indication
For prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness, and vertigo (dizziness caused by other medical problems).
Marezine
Pharmacology
Cyclizine is a piperazine-derivative antihistamine used as an antivertigo/antiemetic agent. Cyclizine is used in the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness. Additionally, it has been used in the management of vertigo in diseases affecting the vestibular apparatus. Although the mechanism by which cyclizine exerts its antiemetic and antivertigo effects has not been fully elucidated, its central anticholinergic properties are partially responsible. The drug depresses labyrinth excitability and vestibular stimulation, and it may affect the medullary chemoreceptor trigger zone. It also possesses anticholinergic, antihistaminic, central nervous system depressant, and local anesthetic effects.
Marezine
Absorption
No information avaliable
Marezine
side effects and Toxicity
No information avaliable
Marezine
Patient Information
No information avaliable
Marezine
Organisms Affected
Humans and other mammals