Wellcome
Brand names,
Wellcome
Analogs
Wellcome
Brand Names Mixture
Wellcome
Chemical_Formula
C18H22N2
Wellcome
RX_link
No information avaliable
Wellcome
fda sheet
Wellcome
msds (material safety sheet)
Wellcome
Synthesis Reference
No information avaliable
Wellcome
Molecular Weight
266.381 g/mol
Wellcome
Melting Point
No information avaliable
Wellcome
H2O Solubility
No information avaliable
Wellcome
State
Solid
Wellcome
LogP
3.338
Wellcome
Dosage Forms
Liquid
Wellcome
Indication
For prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness, and vertigo (dizziness caused by other medical problems).
Wellcome
Pharmacology
Cyclizine is a piperazine-derivative antihistamine used as an antivertigo/antiemetic agent. Cyclizine is used in the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness. Additionally, it has been used in the management of vertigo in diseases affecting the vestibular apparatus. Although the mechanism by which cyclizine exerts its antiemetic and antivertigo effects has not been fully elucidated, its central anticholinergic properties are partially responsible. The drug depresses labyrinth excitability and vestibular stimulation, and it may affect the medullary chemoreceptor trigger zone. It also possesses anticholinergic, antihistaminic, central nervous system depressant, and local anesthetic effects.
Wellcome
Absorption
No information avaliable
Wellcome
side effects and Toxicity
No information avaliable
Wellcome
Patient Information
No information avaliable
Wellcome
Organisms Affected
Humans and other mammals