Ciclizina
Brand names,
Ciclizina
Analogs
Ciclizina
Brand Names Mixture
Ciclizina
Chemical_Formula
C18H22N2
Ciclizina
RX_link
No information avaliable
Ciclizina
fda sheet
Ciclizina
msds (material safety sheet)
Ciclizina
Synthesis Reference
No information avaliable
Ciclizina
Molecular Weight
266.381 g/mol
Ciclizina
Melting Point
No information avaliable
Ciclizina
H2O Solubility
No information avaliable
Ciclizina
State
Solid
Ciclizina
LogP
3.338
Ciclizina
Dosage Forms
Liquid
Ciclizina
Indication
For prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness, and vertigo (dizziness caused by other medical problems).
Ciclizina
Pharmacology
Cyclizine is a piperazine-derivative antihistamine used as an antivertigo/antiemetic agent. Cyclizine is used in the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness. Additionally, it has been used in the management of vertigo in diseases affecting the vestibular apparatus. Although the mechanism by which cyclizine exerts its antiemetic and antivertigo effects has not been fully elucidated, its central anticholinergic properties are partially responsible. The drug depresses labyrinth excitability and vestibular stimulation, and it may affect the medullary chemoreceptor trigger zone. It also possesses anticholinergic, antihistaminic, central nervous system depressant, and local anesthetic effects.
Ciclizina
Absorption
No information avaliable
Ciclizina
side effects and Toxicity
No information avaliable
Ciclizina
Patient Information
No information avaliable
Ciclizina
Organisms Affected
Humans and other mammals